Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesis

Regulator of telomere length 1 (RTEL1) is a DNA helicase protein that has been demonstrated to be required for the maintenance of telomere length and genomic stability. It has also been found to be essential for DNA homologous recombination during DNA repairing. Human RTEL1 genomic locus (20q13.3) i...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoli, Sandhu, Sumit, Nabi, Zinnatun, Ding, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432790/
https://www.ncbi.nlm.nih.gov/pubmed/22238064
http://dx.doi.org/10.1007/s11248-011-9586-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432790/
https://www.ncbi.nlm.nih.gov/pubmed/22238064
http://dx.doi.org/10.1007/s11248-011-9586-7

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