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Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesis
Regulator of telomere length 1 (RTEL1) is a DNA helicase protein that has been demonstrated to be required for the maintenance of telomere length and genomic stability. It has also been found to be essential for DNA homologous recombination during DNA repairing. Human RTEL1 genomic locus (20q13.3) i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432790/ https://www.ncbi.nlm.nih.gov/pubmed/22238064 http://dx.doi.org/10.1007/s11248-011-9586-7 |