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Glucagon secretion and signaling in the development of diabetes

Normal release of glucagon from pancreatic islet α-cells promotes glucose mobilization, which counteracts the hypoglycemic actions of insulin, thereby ensuring glucose homeostasis. In treatment of diabetes aimed at rigorously reducing hyperglycemia to avoid chronic complications, the resulting hypog...

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Detalles Bibliográficos
Autores principales: Gaisano, Herbert Y., MacDonald, Patrick E., Vranic, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432929/
https://www.ncbi.nlm.nih.gov/pubmed/22969729
http://dx.doi.org/10.3389/fphys.2012.00349