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Glucagon secretion and signaling in the development of diabetes
Normal release of glucagon from pancreatic islet α-cells promotes glucose mobilization, which counteracts the hypoglycemic actions of insulin, thereby ensuring glucose homeostasis. In treatment of diabetes aimed at rigorously reducing hyperglycemia to avoid chronic complications, the resulting hypog...
Autores principales: | Gaisano, Herbert Y., MacDonald, Patrick E., Vranic, Mladen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432929/ https://www.ncbi.nlm.nih.gov/pubmed/22969729 http://dx.doi.org/10.3389/fphys.2012.00349 |
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