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A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease

Reactive oxygen species (ROS) play essential roles in cell signaling, survival, and homeostasis. Aberrant ROS lead to disease and contribute to the aging process. Numerous enzymes and vigilant antioxidant pathways are required to regulate ROS for normal cellular health. Mitochondria are a major sour...

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Detalles Bibliográficos
Autores principales: Celotto, Alicia M, Liu, Zhaohui, VanDemark, Andrew P, Palladino, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432965/
https://www.ncbi.nlm.nih.gov/pubmed/22950046
http://dx.doi.org/10.1002/brb3.73