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Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

Uncoupling proteins (UCPs) belong to a large family of mitochondrial solute carriers 25 (SLC25s) localized at the inner mitochondrial membrane. UCPs transport protons directly from the intermembrane space to the matrix. Of five structural homologues (UCP1 to 5), UCP4 and 5 are principally expressed...

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Detalles Bibliográficos
Autores principales: Ramsden, David B, Ho, Philip W-L, Ho, Jessica W-M, Liu, Hui-Fang, So, Danny H-F, Tse, Ho-Man, Chan, Koon-Ho, Ho, Shu-Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432969/
https://www.ncbi.nlm.nih.gov/pubmed/22950050
http://dx.doi.org/10.1002/brb3.55