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Identification of Identical Transcript Changes in Liver and Whole Blood during Acetaminophen Toxicity

The ability to identify mechanisms underlying drug-induced liver injury (DILI) in man has been hampered by the difficulty in obtaining liver tissue from patients. It has recently been proposed that whole blood toxicogenomics may provide a non-invasive means for mechanistic studies of human DILI. How...

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Detalles Bibliográficos
Autores principales: Zhang, Liwen, Bushel, Pierre R., Chou, Jeff, Zhou, Tong, Watkins, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432993/
https://www.ncbi.nlm.nih.gov/pubmed/22973295
http://dx.doi.org/10.3389/fgene.2012.00162