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Urinary Matrix Metalloproteinase Activity in Diabetic Kidney Disease: A Potential Marker of Disease Progression

BACKGROUND: Progressive kidney fibrosis, associated with chronic kidney disease (CKD), results from an imbalance in extracellular matrix (ECM) homeostasis. Reduced matrix metalloproteinases (MMP) activity causing lower clearance of ECM proteins has been implicated mainly through an overproduction of...

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Detalles Bibliográficos
Autores principales: Altemtam, Nagi, Nahas, Meguid El, Johnson, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433015/
https://www.ncbi.nlm.nih.gov/pubmed/22949917
http://dx.doi.org/10.1159/000339645