MAO-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin

Increased oxidative stress in the Parkinsonian substantia nigra is believed to contribute to neurodegeneration, in part due to regionally elevated levels of the enzyme monoamine oxidase B (MAO-B). Increased oxidative stress has also been reported to be associated with the inhibition of E3 ligase act...

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Detalles Bibliográficos
Autores principales: Siddiqui, Almas, Hanson, Ingrid, Andersen, Julie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433084/
https://www.ncbi.nlm.nih.gov/pubmed/22329629
http://dx.doi.org/10.3109/10715762.2012.662277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433084/
https://www.ncbi.nlm.nih.gov/pubmed/22329629
http://dx.doi.org/10.3109/10715762.2012.662277

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