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MAO-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin
Increased oxidative stress in the Parkinsonian substantia nigra is believed to contribute to neurodegeneration, in part due to regionally elevated levels of the enzyme monoamine oxidase B (MAO-B). Increased oxidative stress has also been reported to be associated with the inhibition of E3 ligase act...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Informa Healthcare
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433084/ https://www.ncbi.nlm.nih.gov/pubmed/22329629 http://dx.doi.org/10.3109/10715762.2012.662277 |