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Pro-Inflammatory Cytokine Regulation of P-glycoprotein in the Developing Blood-Brain Barrier

Placental P-glycoprotein (P-gp) acts to protect the developing fetus from exogenous compounds. This protection declines with advancing gestation leaving the fetus and fetal brain vulnerable to these compounds and potential teratogens in maternal circulation. This vulnerability may be more pronounced...

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Detalles Bibliográficos
Autores principales: Iqbal, Majid, Ho, Hay Lam, Petropoulos, Sophie, Moisiadis, Vasilis G., Gibb, William, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433182/
https://www.ncbi.nlm.nih.gov/pubmed/22973436
http://dx.doi.org/10.1371/journal.pone.0043022