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Pro-Inflammatory Cytokine Regulation of P-glycoprotein in the Developing Blood-Brain Barrier
Placental P-glycoprotein (P-gp) acts to protect the developing fetus from exogenous compounds. This protection declines with advancing gestation leaving the fetus and fetal brain vulnerable to these compounds and potential teratogens in maternal circulation. This vulnerability may be more pronounced...
Autores principales: | Iqbal, Majid, Ho, Hay Lam, Petropoulos, Sophie, Moisiadis, Vasilis G., Gibb, William, Matthews, Stephen G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433182/ https://www.ncbi.nlm.nih.gov/pubmed/22973436 http://dx.doi.org/10.1371/journal.pone.0043022 |
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