Polymeric nanoparticles conjugate a novel heptapeptide as an epidermal growth factor receptor-active targeting ligand for doxorubicin

BACKGROUND: This study was performed to develop a functional poly(D,L-lactide-co-glycolide)- poly(ethylene glycol) (PLGA-PEG)-bearing amino-active end group for peptide conjugation. METHODS AND RESULTS: PLGA was preactivated following by copolymerization with PEG diamine. The resulting amphiphilic P...

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Detalles Bibliográficos
Autores principales: Liu, Chia Wen, Lin, Wen Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433327/
https://www.ncbi.nlm.nih.gov/pubmed/22973097
http://dx.doi.org/10.2147/IJN.S32830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433327/
https://www.ncbi.nlm.nih.gov/pubmed/22973097
http://dx.doi.org/10.2147/IJN.S32830

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