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Slings enable neutrophil rolling at high shear

Most leukocytes can roll along the walls of venules at low shear stress (1 dyn/cm(2)), but neutrophils have the ability to roll at 10-fold higher shear stress in microvessels in vivo(1,2). The mechanisms involved in this shear-resistant rolling are known to involve cell flattening(3) and pulling of...

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Detalles Bibliográficos
Autores principales: Sundd, Prithu, Gutierrez, Edgar, Koltsova, Ekaterina K., Kuwano, Yoshihiro, Fukuda, Satoru, Pospieszalska, Maria K., Groisman, Alexander, Ley, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433404/
https://www.ncbi.nlm.nih.gov/pubmed/22763437
http://dx.doi.org/10.1038/nature11248