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Galectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling

PURPOSE: The trabecular meshwork (TM) cell-matrix interactions and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. The current study was designed to evaluate the role of a carbohydrate-binding protein, galectin-8 (Gal8), in TM...

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Detalles Bibliográficos
Autores principales: Diskin, Shiri, Chen, Wei-Sheng, Cao, Zhiyi, Gyawali, Smita, Gong, Haiyan, Soza, Andrea, González, Alfonso, Panjwani, Noorjahan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433423/
https://www.ncbi.nlm.nih.gov/pubmed/22973445
http://dx.doi.org/10.1371/journal.pone.0044400