Secretion of Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1/sFlt1) Requires Arf1, Arf6, and Rab11 GTPases

The soluble form of vascular endothelial growth factor receptor 1 (sVEGFR-1/sFlt1) is generated by alternative splicing of the FLT1 gene. Secretion of sFlt1 from endothelial cells plays an important role in blood vessel sprouting and morphogenesis. However, excess sFlt1 secretion is associated with...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Jae-Joon, Tiwari, Ajit, Inamdar, Shivangi M., Thomas, Christie P., Goel, Apollina, Choudhury, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433446/
https://www.ncbi.nlm.nih.gov/pubmed/22962618
http://dx.doi.org/10.1371/journal.pone.0044572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433446/
https://www.ncbi.nlm.nih.gov/pubmed/22962618
http://dx.doi.org/10.1371/journal.pone.0044572

Ejemplares similares