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Protein Disorder and Short Conserved Motifs in Disordered Regions Are Enriched near the Cytoplasmic Side of Single-Pass Transmembrane Proteins

Intracellular juxtamembrane regions of transmembrane proteins play pivotal roles in cell signalling, mediated by protein-protein interactions. Disordered protein regions, and short conserved motifs within them, are emerging as key determinants of many such interactions. Here, we investigated whether...

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Detalles Bibliográficos
Autores principales: Stavropoulos, Ilias, Khaldi, Nora, Davey, Norman E., O’Brien, Kevin, Martin, Finian, Shields, Denis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433447/
https://www.ncbi.nlm.nih.gov/pubmed/22962613
http://dx.doi.org/10.1371/journal.pone.0044389