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Expression of TRPV1 Channels after Nerve Injury Provides an Essential Delivery Tool for Neuropathic Pain Attenuation

Increased expression of the transient receptor potential vanilloid 1 (TRPV1) channels, following nerve injury, may facilitate the entry of QX-314 into nociceptive neurons in order to achieve effective and selective pain relief. In this study we hypothesized that the level of QX-314/capsaicin (QX-CAP...

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Detalles Bibliográficos
Autores principales: Zakir, Hossain Md., Mostafeezur, Rahman Md., Suzuki, Akiko, Hitomi, Suzuro, Suzuki, Ikuko, Maeda, Takeyasu, Seo, Kenji, Yamada, Yoshiaki, Yamamura, Kensuke, Lev, Shaya, Binshtok, Alexander M., Iwata, Koichi, Kitagawa, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433461/
https://www.ncbi.nlm.nih.gov/pubmed/22962595
http://dx.doi.org/10.1371/journal.pone.0044023