Cargando…

A Novel MMP-2 Inhibitor 3-azidowithaferin A (3-azidoWA) Abrogates Cancer Cell Invasion and Angiogenesis by Modulating Extracellular Par-4

BACKGROUND: Withaferin A, which is a naturally derived steroidal lactone, has been found to prevent angiogenesis and metastasis in diverse tumor models. It has also been recognized by different groups for prominent anti-carcinogenic roles. However, in spite of these studies on withanolides, their de...

Descripción completa

Detalles Bibliográficos
Autores principales: Rah, Bilal, Amin, Hina, Yousuf, Khalid, Khan, Sheema, Jamwal, Gayatri, Mukherjee, Debaraj, Goswami, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433490/
https://www.ncbi.nlm.nih.gov/pubmed/22962598
http://dx.doi.org/10.1371/journal.pone.0044039