Direct observation of mammalian cell growth and size regulation

We introduce a microfluidic system for simultaneously measuring single cell mass and cell cycle progression over multiple generations. We use this system to obtain over 1,000 hours of growth data from mouse lymphoblast and pro-B-cell lymphoid cell lines. Cell lineage analysis revealed a decrease in...

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Detalles Bibliográficos
Autores principales: Son, Sungmin, Tzur, Amit, Weng, Yaochung, Jorgensen, Paul, Kim, Jisoo, Kirschner, Marc W., Manalis, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433595/
https://www.ncbi.nlm.nih.gov/pubmed/22863882
http://dx.doi.org/10.1038/nmeth.2133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433595/
https://www.ncbi.nlm.nih.gov/pubmed/22863882
http://dx.doi.org/10.1038/nmeth.2133

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