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Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men
Common genetic variations in the gene encoding transcription factor 7-like 2 (TCF7L2) reveal the strongest association with type 2-diabetes known to date. These lead to impaired insulin production and output, but the mechanisms of disease remain incompletely known. In this issue of Diabetologia, two...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer-Verlag
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433659/ https://www.ncbi.nlm.nih.gov/pubmed/22864463 http://dx.doi.org/10.1007/s00125-012-2659-1 |