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Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins
Shiga-like toxins and ricin are ribosome-inactivating proteins (RIPs) that are lethal to mammals and pose a global health threat. No clinical vaccines or therapeutics currently exist to protect against these RIPs. Two small molecules (Retro-1 and Retro-2) were discovered with high-throughput screeni...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433688/ https://www.ncbi.nlm.nih.gov/pubmed/22953052 http://dx.doi.org/10.1038/srep00631 |