A stomatin dimer modulates the activity of acid-sensing ion channels

Stomatin proteins oligomerize at membranes and have been implicated in ion channel regulation and membrane trafficking. To obtain mechanistic insights into their function, we determined three crystal structures of the conserved stomatin domain of mouse stomatin that assembles into a banana-shaped di...

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Detalles Bibliográficos
Autores principales: Brand, Janko, Smith, Ewan St J, Schwefel, David, Lapatsina, Liudmila, Poole, Kate, Omerbašić, Damir, Kozlenkov, Alexey, Behlke, Joachim, Lewin, Gary R, Daumke, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433786/
https://www.ncbi.nlm.nih.gov/pubmed/22850675
http://dx.doi.org/10.1038/emboj.2012.203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433786/
https://www.ncbi.nlm.nih.gov/pubmed/22850675
http://dx.doi.org/10.1038/emboj.2012.203

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