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Rapid Identification of Monospecific Monoclonal Antibodies Using a Human Proteome Microarray

To broaden the range of tools available for proteomic research, we generated a library of 16,368 unique full-length human ORFs that are expressible as N-terminal GST-His(6) fusion proteins. Following expression in yeast, these proteins were then individually purified and used to construct a human pr...

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Detalles Bibliográficos
Autores principales: Jeong, Jun Seop, Jiang, Lizhi, Albino, Edisa, Marrero, Josean, Rho, Hee Sool, Hu, Jianfei, Hu, Shaohui, Vera, Carlos, Bayron-Poueymiroy, Diane, Rivera-Pacheco, Zully Ann, Ramos, Leonardo, Torres-Castro, Cecil, Qian, Jiang, Bonaventura, Joseph, Boeke, Jef D., Yap, Wendy Y., Pino, Ignacio, Eichinger, Daniel J., Zhu, Heng, Blackshaw, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433917/
https://www.ncbi.nlm.nih.gov/pubmed/22307071
http://dx.doi.org/10.1074/mcp.O111.016253