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The Proteomic Profile of Circulating Pentraxin 3 (PTX3) Complex in Sepsis Demonstrates the Interaction with Azurocidin 1 and Other Components of Neutrophil Extracellular Traps

Pentraxin 3 (PTX3), a long pentraxin subfamily member in the pentraxin family, plays an important role in innate immunity as a soluble pattern recognition receptor. Plasma PTX3 is elevated in sepsis (∼200 ng/ml) and correlates with mortality. The roles of PTX3 in sepsis, however, are not well unders...

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Detalles Bibliográficos
Autores principales: Daigo, Kenji, Yamaguchi, Naotaka, Kawamura, Takeshi, Matsubara, Koichi, Jiang, Shuying, Ohashi, Riuko, Sudou, Yukio, Kodama, Tatsuhiko, Naito, Makoto, Inoue, Kenji, Hamakubo, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433926/
https://www.ncbi.nlm.nih.gov/pubmed/22278372
http://dx.doi.org/10.1074/mcp.M111.015073