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Methylation by Set9 modulates FoxO3 stability and transcriptional activity

The FoxO family of transcription factors plays an important role in longevity and tumor suppression by regulating the expression of a wide range of target genes. FoxO3 has recently been found to be associated with extreme longevity in humans and to regulate the homeostasis of adult stem cell pools i...

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Detalles Bibliográficos
Autores principales: Calnan, Daniel R., Webb, Ashley E., White, Jamie L., Stowe, Timothy R., Goswami, Tapasree, Shi, Xiaobing, Espejo, Alexsandra, Bedford, Mark T., Gozani, Or, Gygi, Steven P., Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433933/
https://www.ncbi.nlm.nih.gov/pubmed/22820736