Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

Anapleurosis is the filling of the TCA cycle with four-carbon units. The common substrate for both anapleurosis and glucose phosphorylation in bacteria is the terminal glycolytic metabolite, phosphoenolpyruvate (PEP). Here we show that E. coli quickly and almost completely turns off PEP consumption...

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Detalles Bibliográficos
Autores principales: Xu, Yi-Fan, Amador-Noguez, Daniel, Reaves, Marshall Louis, Feng, Xiao-Jiang, Rabinowitz, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433955/
https://www.ncbi.nlm.nih.gov/pubmed/22522319
http://dx.doi.org/10.1038/nchembio.941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433955/
https://www.ncbi.nlm.nih.gov/pubmed/22522319
http://dx.doi.org/10.1038/nchembio.941

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