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A reaction–diffusion mechanism influences cell lineage progression as a basis for formation, regeneration, and stability of intestinal crypts

BACKGROUND: Colon crypts, a single sheet of epithelia cells, consist of a periodic pattern of stem cells, transit-amplifying cells, and terminally differentiated cells that constantly renew and turnover. Experimental evidence suggests that Wnt signaling promotes and regulates stem cell division, dif...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Lander, Arthur D, Nie, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434027/
https://www.ncbi.nlm.nih.gov/pubmed/22849824
http://dx.doi.org/10.1186/1752-0509-6-93