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Engineering of daidzein 3’-hydroxylase P450 enzyme into catalytically self-sufficient cytochrome P450

A cytochrome P450 (CYP) enzyme, 3’-daidzein hydroxylase, CYP105D7 (3’-DH), responsible for daidzein hydroxylation at the 3’-position, was recently reported. CYP105D7 (3’-DH) is a class I type of CYP that requires electrons provided through electron transfer proteins such as ferredoxin and ferredoxin...

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Detalles Bibliográficos
Autores principales: Choi, Kwon-Young, Jung, EunOk, Jung, Da-Hye, An, Byeo-Ri, Pandey, Bishnu Prasad, Yun, Hyungdon, Sung, Changmin, Park, Hyung-Yeon, Kim, Byung-Gee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434051/
https://www.ncbi.nlm.nih.gov/pubmed/22697884
http://dx.doi.org/10.1186/1475-2859-11-81