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Modeling suggests that gene circuit architecture controls phenotypic variability in a bacterial persistence network
BACKGROUND: Bacterial persistence is a non-inherited bet-hedging mechanism where a subpopulation of cells enters a dormant state, allowing those cells to survive environmental stress such as treatment with antibiotics. Persister cells are not mutants; they are formed by natural stochastic variation...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434061/ https://www.ncbi.nlm.nih.gov/pubmed/22607777 http://dx.doi.org/10.1186/1752-0509-6-47 |