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Inclusion bodies as potential vehicles for recombinant protein delivery into epithelial cells

BACKGROUND: We present the potential of inclusion bodies (IBs) as a protein delivery method for polymeric filamentous proteins. We used as cell factory a strain of E. coli, a conventional host organism, and keratin 14 (K14) as an example of a complex protein. Keratins build the intermediate filament...

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Detalles Bibliográficos
Autores principales: Liovic, Mirjana, Ozir, Mateja, Zavec, Apolonija Bedina, Peternel, Spela, Komel, Radovan, Zupancic, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434093/
https://www.ncbi.nlm.nih.gov/pubmed/22624805
http://dx.doi.org/10.1186/1475-2859-11-67