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Inclusion bodies as potential vehicles for recombinant protein delivery into epithelial cells
BACKGROUND: We present the potential of inclusion bodies (IBs) as a protein delivery method for polymeric filamentous proteins. We used as cell factory a strain of E. coli, a conventional host organism, and keratin 14 (K14) as an example of a complex protein. Keratins build the intermediate filament...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434093/ https://www.ncbi.nlm.nih.gov/pubmed/22624805 http://dx.doi.org/10.1186/1475-2859-11-67 |