Impact of signaling microcompartment geometry on GPCR dynamics in live retinal photoreceptors

G protein–coupled receptor (GPCR) cascades rely on membrane protein diffusion for signaling and are generally found in spatially constrained subcellular microcompartments. How the geometry of these microcompartments impacts cascade activities, however, is not understood, primarily because of the ina...

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Detalles Bibliográficos
Autores principales: Najafi, Mehdi, Haeri, Mohammad, Knox, Barry E., Schiesser, William E., Calvert, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434098/
https://www.ncbi.nlm.nih.gov/pubmed/22891277
http://dx.doi.org/10.1085/jgp.201210818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434098/
https://www.ncbi.nlm.nih.gov/pubmed/22891277
http://dx.doi.org/10.1085/jgp.201210818

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