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Impact of signaling microcompartment geometry on GPCR dynamics in live retinal photoreceptors
G protein–coupled receptor (GPCR) cascades rely on membrane protein diffusion for signaling and are generally found in spatially constrained subcellular microcompartments. How the geometry of these microcompartments impacts cascade activities, however, is not understood, primarily because of the ina...
Autores principales: | Najafi, Mehdi, Haeri, Mohammad, Knox, Barry E., Schiesser, William E., Calvert, Peter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434098/ https://www.ncbi.nlm.nih.gov/pubmed/22891277 http://dx.doi.org/10.1085/jgp.201210818 |
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