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Structural changes during HCN channel gating defined by high affinity metal bridges

Hyperpolarization-activated cyclic nucleotide–sensitive nonselective cation (HCN) channels are activated by membrane hyperpolarization, in contrast to the vast majority of other voltage-gated channels that are activated by depolarization. The structural basis for this unique characteristic of HCN ch...

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Detalles Bibliográficos
Autores principales: Kwan, Daniel C.H., Prole, David L., Yellen, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434101/
https://www.ncbi.nlm.nih.gov/pubmed/22930802
http://dx.doi.org/10.1085/jgp.201210838