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Structural changes during HCN channel gating defined by high affinity metal bridges
Hyperpolarization-activated cyclic nucleotide–sensitive nonselective cation (HCN) channels are activated by membrane hyperpolarization, in contrast to the vast majority of other voltage-gated channels that are activated by depolarization. The structural basis for this unique characteristic of HCN ch...
Autores principales: | Kwan, Daniel C.H., Prole, David L., Yellen, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434101/ https://www.ncbi.nlm.nih.gov/pubmed/22930802 http://dx.doi.org/10.1085/jgp.201210838 |
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