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Kinetics of T Helper Subsets and Associated Cytokines Correlate Well with the Clinical Activity of Graft-Versus-Host Disease

BACKGROUND: CD4(+)interferon (IFN)-γ(+) T cell (Th1) and CD4(+)interleukin (IL)-4(+) T cell (Th2) polarizations are crucial in the pathogenesis of graft-versus-host disease (GVHD). However, this hypothesis is largely based on animal experiments of Parent-into-F1 GVHD model. The causal relationship b...

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Detalles Bibliográficos
Autores principales: Yeh, Su-Peng, Liao, Yu-Min, Lo, Wen-Jyi, Lin, Chiao-Lin, Bai, Li-Yuan, Lin, Chen-Yuan, Hsieh, Ching-Yun, Chang, Yu-Chien, Huang, Yu-Ting, Chiu, Chang-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434128/
https://www.ncbi.nlm.nih.gov/pubmed/22957070
http://dx.doi.org/10.1371/journal.pone.0044416