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Cilostazol Prevents Endothelin-Induced Smooth Muscle Constriction and Proliferation

Cilostazol is a phosphodiesterase inhibitor that has been shown to inhibit platelet activation. Endothelin is known to be the most potent endogenous growth promoting and vasoactive peptide. In patients and animal models with stroke, the level of circulating endothelin increases and complicates the r...

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Detalles Bibliográficos
Autores principales: Kawanabe, Yoshifumi, Takahashi, Maki, Jin, Xingjian, Abdul-Majeed, Shakila, Nauli, Andromeda M., Sari, Youssef, Nauli, Surya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434142/
https://www.ncbi.nlm.nih.gov/pubmed/22957074
http://dx.doi.org/10.1371/journal.pone.0044476