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Antibody Protection Reveals Extended Epitopes on the Human TSH Receptor
Stimulating, and some blocking, antibodies to the TSH receptor (TSHR) have conformation-dependent epitopes reported to involve primarily the leucine rich repeat region of the ectodomain (LRD). However, successful crystallization of TSHR residues 22–260 has omitted important extracellular non-LRD res...
Autores principales: | Latif, Rauf, Teixeira, Avelino, Michalek, Krzysztof, Ali, M. Rejwan, Schlesinger, Max, Baliram, Ramkumarie, Morshed, Syed A., Davies, Terry F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434159/ https://www.ncbi.nlm.nih.gov/pubmed/22957097 http://dx.doi.org/10.1371/journal.pone.0044669 |
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