Optimal Isolation of Functional Foxp3(+) Induced Regulatory T Cells Using DEREG Mice

Foxp3 reporter mice including DEREG (DEpletion of REGulatory T cells) mice have greatly helped in exploring the biology of Foxp3(+) Tregs. DEREG mice express a DTR-eGFP fusion protein under the control of a bacterial artificial chromosome (BAC)-encoded Foxp3 promoter, allowing the viable isolation a...

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Detalles Bibliográficos
Autores principales: Baru, Abdul Mannan, Untucht, Christopher, Ganesh, Venkateswaran, Hesse, Christina, Mayer, Christian T., Sparwasser, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434173/
https://www.ncbi.nlm.nih.gov/pubmed/22957107
http://dx.doi.org/10.1371/journal.pone.0044760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434173/
https://www.ncbi.nlm.nih.gov/pubmed/22957107
http://dx.doi.org/10.1371/journal.pone.0044760

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