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Agnathan VIP, PACAP and Their Receptors: Ancestral Origins of Today's Highly Diversified Forms

VIP and PACAP are pleiotropic peptides belonging to the secretin superfamily of brain-gut peptides and interact specifically with three receptors (VPAC(1), PAC(1) and VPAC(2)) from the class II B G protein-coupled receptor family. There is immense interest regarding their molecular evolution which i...

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Detalles Bibliográficos
Autores principales: Ng, Stephanie Y. L., Chow, Billy K. C., Kasamatsu, Jun, Kasahara, Masanori, Lee, Leo T. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434177/
https://www.ncbi.nlm.nih.gov/pubmed/22957100
http://dx.doi.org/10.1371/journal.pone.0044691