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Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model

Mice bearing a “humanized” immune system are valuable tools to experimentally manipulate human cells in vivo and facilitate disease models not normally possible in laboratory animals. Here we describe a form of GVHD that develops in NOD/SCID mice reconstituted with human fetal bone marrow, liver and...

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Detalles Bibliográficos
Autores principales: Greenblatt, Matthew B., Vbranac, Vladimir, Tivey, Trevor, Tsang, Kelly, Tager, Andrew M., Aliprantis, Antonios O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434179/
https://www.ncbi.nlm.nih.gov/pubmed/22957096
http://dx.doi.org/10.1371/journal.pone.0044664