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Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model
Mice bearing a “humanized” immune system are valuable tools to experimentally manipulate human cells in vivo and facilitate disease models not normally possible in laboratory animals. Here we describe a form of GVHD that develops in NOD/SCID mice reconstituted with human fetal bone marrow, liver and...
Autores principales: | Greenblatt, Matthew B., Vbranac, Vladimir, Tivey, Trevor, Tsang, Kelly, Tager, Andrew M., Aliprantis, Antonios O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434179/ https://www.ncbi.nlm.nih.gov/pubmed/22957096 http://dx.doi.org/10.1371/journal.pone.0044664 |
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