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Transposable Elements in TDP-43-Mediated Neurodegenerative Disorders

Elevated expression of specific transposable elements (TEs) has been observed in several neurodegenerative disorders. TEs also can be active during normal neurogenesis. By mining a series of deep sequencing datasets of protein-RNA interactions and of gene expression profiles, we uncovered extensive...

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Detalles Bibliográficos
Autores principales: Li, Wanhe, Jin, Ying, Prazak, Lisa, Hammell, Molly, Dubnau, Josh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434193/
https://www.ncbi.nlm.nih.gov/pubmed/22957047
http://dx.doi.org/10.1371/journal.pone.0044099