Depletion of HDAC6 Enhances Cisplatin-Induced DNA Damage and Apoptosis in Non-Small Cell Lung Cancer Cells

Histone deacetylase inhibitors (HDACi) are promising therapeutic agents which are currently used in combination with chemotherapeutic agents in clinical trials for cancer treatment including non-small cell lung cancer (NSCLC). However, the mechanisms underlying their anti-tumor activities remain elu...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Xiang, Shengyan, Williams, Kendra A., Dong, Huiqin, Bai, Wenlong, Nicosia, Santo V., Khochbin, Saadi, Bepler, Gerold, Zhang, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434198/
https://www.ncbi.nlm.nih.gov/pubmed/22957056
http://dx.doi.org/10.1371/journal.pone.0044265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434198/
https://www.ncbi.nlm.nih.gov/pubmed/22957056
http://dx.doi.org/10.1371/journal.pone.0044265

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