Depletion of the C. elegans NAC Engages the Unfolded Protein Response, Resulting in Increased Chaperone Expression and Apoptosis

The nascent polypeptide-associated complex (NAC) is a highly conserved heterodimer important for metazoan development, but its molecular function is not well understood. Recent evidence suggests the NAC is a component of the cytosolic chaperone network that interacts with ribosomal complexes and the...

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Detalles Bibliográficos
Autores principales: Arsenovic, Paul T., Maldonado, Anthony T., Colleluori, Vaughn D., Bloss, Tim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434205/
https://www.ncbi.nlm.nih.gov/pubmed/22957041
http://dx.doi.org/10.1371/journal.pone.0044038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434205/
https://www.ncbi.nlm.nih.gov/pubmed/22957041
http://dx.doi.org/10.1371/journal.pone.0044038

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