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Depletion of the C. elegans NAC Engages the Unfolded Protein Response, Resulting in Increased Chaperone Expression and Apoptosis

The nascent polypeptide-associated complex (NAC) is a highly conserved heterodimer important for metazoan development, but its molecular function is not well understood. Recent evidence suggests the NAC is a component of the cytosolic chaperone network that interacts with ribosomal complexes and the...

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Detalles Bibliográficos
Autores principales:	Arsenovic, Paul T., Maldonado, Anthony T., Colleluori, Vaughn D., Bloss, Tim A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434205/ https://www.ncbi.nlm.nih.gov/pubmed/22957041 http://dx.doi.org/10.1371/journal.pone.0044038

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