A Practical Simulation Method to Calculate Sample Size of Group Sequential Trials for Time-to-Event Data under Exponential and Weibull Distribution

Group sequential design has been widely applied in clinical trials in the past few decades. The sample size estimation is a vital concern of sponsors and investigators. Especially in the survival group sequential trials, it is a thorny question because of its ambiguous distributional form, censored...

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Detalles Bibliográficos
Autores principales: Jiang, Zhiwei, Wang, Ling, Li, Chanjuan, Xia, Jielai, Jia, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434206/
https://www.ncbi.nlm.nih.gov/pubmed/22957040
http://dx.doi.org/10.1371/journal.pone.0044013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434206/
https://www.ncbi.nlm.nih.gov/pubmed/22957040
http://dx.doi.org/10.1371/journal.pone.0044013

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