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A Novel Computational Strategy to Identify A-to-I RNA Editing Sites by RNA-Seq Data: De Novo Detection in Human Spinal Cord Tissue

RNA editing is a post-transcriptional process occurring in a wide range of organisms. In human brain, the A-to-I RNA editing, in which individual adenosine (A) bases in pre-mRNA are modified to yield inosine (I), is the most frequent event. Modulating gene expression, RNA editing is essential for ce...

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Detalles Bibliográficos
Autores principales: Picardi, Ernesto, Gallo, Angela, Galeano, Federica, Tomaselli, Sara, Pesole, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434223/
https://www.ncbi.nlm.nih.gov/pubmed/22957051
http://dx.doi.org/10.1371/journal.pone.0044184