Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury

Angiotensin II causes cardiovascular injury in part by aldosterone-induced mineralocorticoid receptor activation, and it can also activate the mineralocorticoid receptor in the absence of aldosterone in vitro. Here we tested whether endogenous aldosterone contributes to angiotensin II/salt-induced c...

Descripción completa

Detalles Bibliográficos
Autores principales: Luther, James M., Luo, Pengcheng, Wang, Zuofei, Cohen, Samuel E., Kim, Hyung-Suk, Fogo, Agnes B., Brown, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434275/
https://www.ncbi.nlm.nih.gov/pubmed/22622494
http://dx.doi.org/10.1038/ki.2012.170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434275/
https://www.ncbi.nlm.nih.gov/pubmed/22622494
http://dx.doi.org/10.1038/ki.2012.170

Ejemplares similares